Product Name :
AI-10-47
Description:
AI-10-47 is a small molecule inhibitor of CBFβ-RUNX binding, with an IC50 of 3.2 μM.
CAS:
1256094-31-1
Molecular Weight:
279.22
Formula:
C13H8F3N3O
Chemical Name:
2-(pyridin-2-yl)-6-(trifluoromethoxy)-1H-1,3-benzodiazole
Smiles :
FC(F)(F)OC1=CC2NC(=NC=2C=C1)C1=CC=CC=N1
InChiKey:
JSNWHSDKJSOXET-UHFFFAOYSA-N
InChi :
InChI=1S/C13H8F3N3O/c14-13(15,16)20-8-4-5-9-11(7-8)19-12(18-9)10-3-1-2-6-17-10/h1-7H,(H,18,19)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{NNZ 2591} site|{NNZ 2591} Protocol|{NNZ 2591} In Vitro|{NNZ 2591} supplier|{NNZ 2591} Epigenetic Reader Domain}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
AI-10-47 is a small molecule inhibitor of CBFβ-RUNX binding, with an IC50 of 3.2 μM.|Product information|CAS Number: 1256094-31-1|Molecular Weight: 279.22|Formula: C13H8F3N3O|Chemical Name: 2-(pyridin-2-yl)-6-(trifluoromethoxy)-1H-1,3-benzodiazole|Smiles: FC(F)(F)OC1=CC2NC(=NC=2C=C1)C1=CC=CC=N1|InChiKey: JSNWHSDKJSOXET-UHFFFAOYSA-N|InChi: InChI=1S/C13H8F3N3O/c14-13(15,16)20-8-4-5-9-11(7-8)19-12(18-9)10-3-1-2-6-17-10/h1-7H,(H,18,19)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 100 mg/mL (358.{{Cetirizine} site|{Cetirizine} Histamine Receptor|{Cetirizine} Purity & Documentation|{Cetirizine} In Vitro|{Cetirizine} manufacturer|{Cetirizine} Epigenetics} 14 mM; Need ultrasonic).PMID:23557924 |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|AI-10-47 (10 μM) weakly inhibits CBFβ-RUNX binding. AI-10-47 significantly inhibits ME-1, TUR, M0-91, THP-1 and U937 cell growth.|Products are for research use only. Not for human use.|