Product Name :
Cleistanthin B
Description:
Cleistanthin B (Diphyllin O-glucoside) is an orally active arylnaphthalene lignan lactone glycoside. Cleistanthin B exhibits anti-SARS-CoV-2 effects in Vero cells, with EC50 of 6.51 µM. Cleistanthin B also exhibits antitumor, diuretic and antihypertensive effects in vivo.
CAS:
30021-77-3
Molecular Weight:
542.49
Formula:
C27H26O12
Chemical Name:
9-(2H-1,3-benzodioxol-5-yl)-6,7-dimethoxy-4-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1H,3H-naphtho[2,3-c]furan-1-one
Smiles :
COC1=CC2=C(C3C(=O)OCC=3C(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)=C2C=C1OC)C1=CC=C2OCOC2=C1
InChiKey:
BJGIWVGXMRUMNA-WBYCZGBQSA-N
InChi :
InChI=1S/C27H26O12/c1-33-16-6-12-13(7-17(16)34-2)25(39-27-24(31)23(30)22(29)19(8-28)38-27)14-9-35-26(32)21(14)20(12)11-3-4-15-18(5-11)37-10-36-15/h3-7,19,22-24,27-31H,8-10H2,1-2H3/t19-,22-,23+,24-,27+/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Carotuximab} MedChemExpress|{Carotuximab} Stem Cell/Wnt|{Carotuximab} NF-κB|{Carotuximab} Biological Activity|{Carotuximab} In Vivo|{Carotuximab} manufacturer}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Cleistanthin B (Diphyllin O-glucoside) is an orally active arylnaphthalene lignan lactone glycoside. Cleistanthin B exhibits anti-SARS-CoV-2 effects in Vero cells, with EC50 of 6.51 µM. Cleistanthin B also exhibits antitumor, diuretic and antihypertensive effects in vivo.|Product information|CAS Number: 30021-77-3|Molecular Weight: 542.49|Formula: C27H26O12|Chemical Name: 9-(2H-1,3-benzodioxol-5-yl)-6,7-dimethoxy-4-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1H,3H-naphtho[2,3-c]furan-1-one|Smiles: COC1=CC2=C(C3C(=O)OCC=3C(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)=C2C=C1OC)C1=CC=C2OCOC2=C1|InChiKey: BJGIWVGXMRUMNA-WBYCZGBQSA-N|InChi: InChI=1S/C27H26O12/c1-33-16-6-12-13(7-17(16)34-2)25(39-27-24(31)23(30)22(29)19(8-28)38-27)14-9-35-26(32)21(14)20(12)11-3-4-15-18(5-11)37-10-36-15/h3-7,19,22-24,27-31H,8-10H2,1-2H3/t19-,22-,23+,24-,27+/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Pyrroloquinoline quinone} MedChemExpress|{Pyrroloquinoline quinone} Metabolic Enzyme/Protease|{Pyrroloquinoline quinone} Purity & Documentation|{Pyrroloquinoline quinone} Description|{Pyrroloquinoline quinone} supplier|{Pyrroloquinoline quinone} Cancer} |Shelf Life: ≥12 months if stored properly.PMID:25027343 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Cleistanthin B exhibits anti-SARS-CoV-2 effects in Vero cells, with EC50 of 6.51 µM. Cleistanthin B shows no cytotoxic to Vero cells in concentrations up to 100 µM.|In Vivo:|Cleistanthin B (25-100 mg/kg; p.o. for 10 dys) has antitumor activity against EAC and DAL tumor mice but it is not effective against solid tumor.|Products are for research use only. Not for human use.|