Sibility study for the evaluation of morphological pattern of neoangiogenesis in human colorectal cancer applying confocal laser endomicroscopy and targeted anti CD antibodies. United European Gastroenterology Journal ; (Supplement. Disclosure of Interest: None declaredP Ribocil site endoscopic MANAGEMENT OF POSTOPERATIVE LEAKAGES AND FISTULAS After ESOPHAGEAL ONCOLOGIC SURGERY: EVALUATION OF EFFICACY Inside a Significant RETROSPECTIVE STUDY C. Servajean,J.M. Gonzalez,M. Gasmi,B. X. D’Journo,J.C. Grimaud,M. Barthet Gastroenterology,Thoracic Surgery,APHM,North Hospital,Marseille,France Speak to Email Address: jmgonzayahoo.fr Introduction: Anastomotic leakages or fistulas are among probably the most common and serious complications of esophagectomy for esophageal cancer,with higher grade of mortality. Not too long ago the endoscopic management has taken a expanding place in the therapy of digestive postoperative complications . The aim of this study was to evaluate the effectiveness and the characteristics in the endoscopic management in this indication. Aims Methods: This is a monocentric study on consecutive sufferers treated surgically in our institution amongst and for esophageal carcinomas. Throughout this period,on individuals operated,created postoperative fistulas or leakages (endoscopically managed and included within this study. All the procedures have been performed in our endoscopy unit,by interventional endoscopists,in intubated patients below general anesthesia,utilizing a large operating channel gastroscope mm,Pentax,Japan) and fluoroscopy. The individuals were systematically controlled endoscopically weeks soon after the endoscopic treatment to verify the efficacy out and to evaluate the need to have for an further remedy. The primary or secondary efficacy,the time in between surgery,diagnostic and endoscopy,the amount of procedures,the material utilised (stents,clips,or drains),the complications,along with the death rate were recorded,and uni and multivariate evaluation was carried out to ascertain predictive aspects of good results. Benefits: There have been girls and males,with a median age of . years . . The surgical methods were in majority LewisSanti for . of instances,Akiyama for . . . patients have undergone neoadjuvant chemo radiation therapy and . were hospitalized in intensive care unit. The median delay in between surgery and 1st endoscopy PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/26212255 was . days . from the patients had been treated utilizing metallic (double kind) esophageal stents,with a removability price of along with a migration price of . The other ones have been treated by Overthescope clips,nasocystic drain or combined method. The mean quantity of endoscopy per patient was . . ,having a mean quantity of . . stents placed. The principal efficacy in the endoscopic therapy was . ,the final efficacy was . . The mortality rate in patients endoscopically managed was ,none becoming connected to procedures. No predictive risk element of results or failure on the endoscopic treatment (CRT,sort of surgery,fistula size,age. .) may be identified in univariate also as in multivariate analysis. Conclusion: The endoscopic management of leakages or fistulas following esophageal surgery is feasible,and bring about an general effectiveness price of . . Perforation essential surgery in situations though was managed conservatively inside the remaining. No mortality associated towards the procedure was observed. Histology has demonstrated intramucosal cancer or submucosal cancer in situations and surgery was expected because of sophisticated histology in patients The imply followup was . months with patients lost for the duration of followup and.