This alternative product is especially attractive in light of the latest demonstration that WNT5A inhibits beta-catenin signaling in mouse cells lacking ROR1 and ROR2, the receptors proposed to transduce a signal that antagonizes beta-catenin signaling

Other people have identified the inaccessibility of human Wnts as a crucial barrier to conquer, in particular as pathway modulators enter scientific trials. For instance, a new depository of expression…