Diseases constituted 9 of all deaths among children <5 years old in 2015.4 Although the burden of diarrheal diseases is much lower in developed countries, it is an important public health problem in low- and middle-income countries because the disease is particularly dangerous for young children, who are more susceptible to dehydration and nutritional losses in those settings.5 In Bangladesh, the burden of diarrheal diseases is significant among children <5 years old.6 Global estimates of the mortality resulting from diarrhea have shown a steady decline since the 1980s. However, despite all advances in health technology, improved management, and increased use of oral rehydrationtherapy, diarrheal diseases are also still a leading cause of public health concern.7 Moreover, morbidity caused by diarrhea has not declined as rapidly as mortality, and global estimates remain at between 2 and 3 episodes of diarrhea annually for children <5 years old.8 There are several studies assessing the prevalence of childhood diarrhea in children <5 years of age. However, in Bangladesh, information on the age-specific prevalence rate of childhood diarrhea is still limited, although such studies are vital for informing policies and allowing international comparisons.9,10 Clinically speaking, diarrhea is an alteration in a normal bowel movement characterized by an increase in theInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh 2 University of Strathclyde, Glasgow, UK Corresponding Author: Abdur Razzaque Sarker, Health Economics and Financing Research, International Centre for Diarrhoeal Disease Research, 68, Shaheed Tajuddin Sarani, Dhaka 1212, Bangladesh. Email: [email protected] Commons Non Commercial CC-BY-NC: a0023781 This short article is distributed beneath the terms with the Creative Commons Attribution-NonCommercial three.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which ENMD-2076 permits noncommercial use, reproduction and distribution in the work devoid of additional permission provided the original operate is attributed as specified around the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).2 water content, volume, or frequency of stools.11 A lower in consistency (ie, soft or liquid) and a rise inside the frequency of bowel movements to 3 stools per day have usually been employed as a definition for epidemiological investigations. Determined by a community-based study viewpoint, diarrhea is defined as no less than three or additional loose stools within a 24-hour period.12 A diarrheal episode is viewed as because the passage of three or much more loose or liquid stools in 24 hours prior to presentation for care, that is considered essentially the most practicable in kids and adults.13 Nevertheless, prolonged and persistent diarrhea can last amongst 7 and 13 days and at least 14 days, respectively.14,15 The disease is extremely sensitive to climate, showing seasonal variations in various web-sites.16 The climate sensitivity of diarrheal disease is consistent with observations of the direct effects of climate variables on the causative agents. Temperature and relative humidity possess a direct influence around the rate of replication of bacterial and protozoan pathogens and on the survival of enteroviruses in the X-396 site environment.17 Health care journal.pone.0169185 looking for is recognized to become a outcome of a complex behavioral approach that may be influenced by quite a few elements, including socioeconomic and demographic and characteristics, perceived need, accessibility, and service availability.Diseases constituted 9 of all deaths among children <5 years old in 2015.4 Although the burden of diarrheal diseases is much lower in developed countries, it is an important public health problem in low- and middle-income countries because the disease is particularly dangerous for young children, who are more susceptible to dehydration and nutritional losses in those settings.5 In Bangladesh, the burden of diarrheal diseases is significant among children <5 years old.6 Global estimates of the mortality resulting from diarrhea have shown a steady decline since the 1980s. However, despite all advances in health technology, improved management, and increased use of oral rehydrationtherapy, diarrheal diseases are also still a leading cause of public health concern.7 Moreover, morbidity caused by diarrhea has not declined as rapidly as mortality, and global estimates remain at between 2 and 3 episodes of diarrhea annually for children <5 years old.8 There are several studies assessing the prevalence of childhood diarrhea in children <5 years of age. However, in Bangladesh, information on the age-specific prevalence rate of childhood diarrhea is still limited, although such studies are vital for informing policies and allowing international comparisons.9,10 Clinically speaking, diarrhea is an alteration in a normal bowel movement characterized by an increase in theInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh 2 University of Strathclyde, Glasgow, UK Corresponding Author: Abdur Razzaque Sarker, Health Economics and Financing Research, International Centre for Diarrhoeal Disease Research, 68, Shaheed Tajuddin Sarani, Dhaka 1212, Bangladesh. Email: [email protected] Commons Non Commercial CC-BY-NC: a0023781 This article is distributed below the terms of your Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits noncommercial use, reproduction and distribution from the perform without the need of additional permission supplied the original function is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).2 water content material, volume, or frequency of stools.11 A lower in consistency (ie, soft or liquid) and a rise in the frequency of bowel movements to 3 stools per day have often been used as a definition for epidemiological investigations. Determined by a community-based study point of view, diarrhea is defined as at least 3 or extra loose stools inside a 24-hour period.12 A diarrheal episode is regarded as as the passage of 3 or extra loose or liquid stools in 24 hours prior to presentation for care, which can be regarded essentially the most practicable in children and adults.13 Having said that, prolonged and persistent diarrhea can last between 7 and 13 days and no less than 14 days, respectively.14,15 The disease is extremely sensitive to climate, showing seasonal variations in numerous web pages.16 The climate sensitivity of diarrheal illness is consistent with observations on the direct effects of climate variables around the causative agents. Temperature and relative humidity have a direct influence around the rate of replication of bacterial and protozoan pathogens and around the survival of enteroviruses in the environment.17 Health care journal.pone.0169185 seeking is recognized to become a result of a complex behavioral approach which is influenced by many components, which includes socioeconomic and demographic and qualities, perceived require, accessibility, and service availability.