Product Name :
Human HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Tetramer Protein 3384
express system :
HEK293
Product tag :
C-His-Avi
Purity:
> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Background:
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
Molecular Weight:
The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reducing (N) condition based on Tris-Bis PAGE result.
Available Size :
100 µg, 500 µg
Endotoxin:
Less than 1EU per ug by the LAL method.
Form :
Lyophilized
Storage Instructions :
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer:
Shipped at ambient temperature.
Additional Information:
accession AAV53343(HLA-A*11:01)&P61769(B2M)&VVVGAVGVGK|express systemHEK293|product tagC-His-Avi|purity> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC|backgroundKirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.|molecular weightThe protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reducing (N) condition based on Tris-Bis PAGE result.|available size100 g, 500 g|endotoxinLess than 1EU per ug by the LAL method.|Human HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Tetramer Protein 3384proteinSize and concentration100, 500g and lyophilizedFormLyophilizedStorage InstructionsValid for 12 months from date of receipt when stored at -80C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.Storage bufferShipped at ambient temperature.Purity> 95% as determined by Tris-Bis PAGEtarget relevanceNo information|
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