Product Name :
1-Methylindole-3-carboxaldehyde, 98+%
Synonym:
IUPAC Name :
1-methyl-1H-indole-3-carbaldehyde
CAS NO.:
19012-03-4
Molecular Weight :
Molecular formula:
C10H9NO
Smiles:
CN1C=C(C=O)C2=CC=CC=C12
Description:
1-Methylindole-3-carboxaldehyde is used as a reactant for preparation of nitroolefins and β-nitroalcohols via microwave- or ultrasound-assisted Henry reactions, reactant for synthesis of quinolinones via three-component Ugi reaction, reactant for synthesis of α-ketoamides as inhibitors of Dengue virus protease with antiviral activity in cell-culture, reactant for preparation of thiazolopyrimidinones as inhibitors of Bcl-2 proteins, reactant for preparation of vinylindoles via Peterson olefination or olefination with Nysted reagent, reactant for preparation of indolyl alkenes from microwave-enhanced Knoevenagel condensation as antibacterial agents 1-Methylindole-3-carboxaldehyde may be used in the synthesis of (Z)-3-(1-methyl-1H-indol-3-yl)-2-(thiophen-3-yl)acrylonitrile, via base-catalyzed condensation with thiophene-3-acetonitrile.Sunitinib Malate It was also used in the preparation of monomer, required for the synthesis of poly(3-vinyl-1-methylindole).L-Leucine PMID:23554582